MTHFR: 4 Things to Consider Before Taking Folate - Doctor Doni
MTHFR: 4 Things to Consider Before Taking Folate - Doctor Doni
Dec 20, 2017
doctordoni.com
Folic acid is the synthetic form of folate. Over 50% of the population has MTHFR gene mutations and cannot process folic acid properly which then becomes toxic to the body. That’s because MTHFR mutations have a hard time converting folic acid so the body can use it. It’s all about homocysteine. MTHFR SNPs lack the enzymes to break down the levels in the body. Folate (natural form of B9) is needed to do this. Folic acid (synthetic form of B9) becomes toxic to the body. Symptoms of MTHFR mutations
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Folate is essential for methylation, thyroid function, and overall health. But there’s a lot of confusion about the different forms, especially if you’ve heard about MTHFR gene variations. Here’s what you should know: * Folate is the natural form in foods. * Folic acid is the common synthetic form in fortified foods and > supplements. * MTHFR variants are very common—up to 40% of people—but most > don’t cause problems. * Poor methylation shows up as high homocysteine (>12μmol/L), not > just on a
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We need homeostasis in the folate pathway to biochemically avoid cancer (as a mechanism). The forms of folate all act in different pathways. Methyl folates perform in methylation. Formyl forms perform in cell turnover. Folinic acid is a FORMYL form of folate. It’s already past the decision point of which folate is produced. It’s irreversible after that (except for extreme measures but why would you ever intentionally max out cell turnover knowing that’ll mess with this balance and turn carcinoge
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