Medusa's Cayenne Pepper Hot Sauce Recipe. This is one of my pearls, a proprietary blend that’s more of a seasoning than a hot sauce. It's the secret ingredient in almost all of my recipes, and today, I'm giving you the recipe so you can make it at home. The base is simple: vinegar, salt, and cayenne pepper. From there, you can make it your own. INGREDIENTS: 1 lb cayenne pepper 4 oz by weight dried chiles (I used Morita, Guajillo, Ancho, California ancho, Arbol, Farm Peppers, New Mexico dried chi