BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

The activation and polarization of T cells play a crucial role in atherosclerosis and dictate athero-inflammation. The epigenetic enzyme EZH2 (enhancer of zeste homolog 2) mediates the H3K27me3 ...

The heart is a highly sex-biased organ, as sex shapes innumerable aspects of heart health and disease. Sex chromosomes and sex hormones —testosterone, progesterone, and estrogen— establish and ...

Suboptimal vascular risk factor screening after pregnancy-related hypertension or diabetes is a missed opportunity for cardiovascular prevention. Multifaceted strategies to improve screening, ...

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Hypertension in pregnancy contributes substantially to maternal morbidity and mortality, persistent hypertension, and rehospitalization. Hypertensive disorders of pregnancy are also associated with a ...

When direct oral anticoagulants (DOACs) were developed, they were meant to entirely substitute vitamin K antagonists (VKAs) in the prevention of thromboembolism and stroke in patients with atrial ...

Department of Pharmacy and Institute of Inflammation, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital (X.H., Y.Z., Y.W., G.L.) Zhejiang Provincial Key Laboratory of Laboratory ...

Dilated cardiomyopathy (DCM) appears to be diagnosed twice as often in male than in female patients. This could be attributed to underdiagnosis in female patients or sex differences in susceptibility.

Department of Internal Medicine (C.J., E.J.L.), Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of ...