Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

Major challenges remain to precisely detect low-abundance proteins rapidly and cost-effectively from diverse biofluids. Here, we present a gold nanoparticle (AuNP)-supported, rapid electronic ...

This study discovered a new thermocatalytic reaction of NO-to-NH3 synthesis to solve nitric oxide pollution and low NH3 synthesis efficiency. Solid-solution OsxPt1–x/γ-Al2O3 exhibited an outstanding ...

A facile asymmetric synthesis of α,α-disubstituted amino acid derivatives was achieved via gold redox catalysis. The in situ formed aryl gold(III) served as the key intermediate toward alkyne ...

Au nanoclusters (NCs), with discrete electronic structures and tunable properties, are promising building blocks for nanoelectronics. However, maximizing their potential requires a deeper ...

The high clinical failure rate of small-molecule drugs is inarguably attributable to the lack of reliable predictions of chemical structure–efficacy–toxicity relationships that are applicable to ...

Correction to “Stealth Polydopamine-Based Nanoparticles with Red Blood Cell Membrane for the Chemo-Photothermal Therapy of Cancer” ...

Herein, we investigated to which extent metallic nanoparticles (MNPs) affect the trophic transfer of other coexisting MNPs from lettuce to terrestrial snails and the associated tissue-specific ...

Noncanonical nucleic acid conformations like G-quadruplexes and i-motifs are key regulators of gene function, genome stability, and drug action. Their structural dynamics in extreme conditions of high ...

Low loose bulk density, a characteristic commonly observed in large accumulations of needle-like crystals, has caused numerous issues in both production processes and daily life. Antisolvent ...

Substituted cyclic alcohol is one of the pharmaceutically essential scaffolds. Here, we report photoredox/cobalt-catalyzed reductive cyclization of alkynals using H2O for the catalyst turnover. This ...

Phototherapy is an effective strategy to control Candida albicans (C. albicans) infection without raising the concern of drug resistance. Despite its effectiveness, a higher dose of phototherapeutic ...