Publishes original research, insights and opinions on evidence-based research. Focuses on the tools, methods, and concepts that are central to practising evidence-based medicine.

. Lan AJ, Colford JM Jr. The impact of dosing frequency on the efficacy of 10-day penicillin or amoxicillin therapy for streptococcal tonsillopharyngitis: a meta-analysis . Pediatrics 2000 Feb; 105 ...

Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, ...

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia. Design Our study design was a ...

From promise to practice: challenges and pitfalls in the evaluation of large language models for data extraction in evidence synthesis ...

Health literacy demands placed on patients and consumers are amplified in low-value care contexts and must be addressed as a system and organisational priority, argue Danielle Muscat and colleagues . ...

Healthcare delivery is being transformed by the rapid growth of data, advancements in artificial intelligence (AI) and other technologies. In healthcare, obtaining real-world data can be ...

Objective This study evaluates whether Taiwan’s national oral cancer screening programme, implemented in 1999, has led to a ...

In 20 years of researching and teaching health risk communication methods, the most common question we get is: how should I communicate this [adverse event risk, survival probability, etc.] so that ...

A systematic review identifies, appraises and synthesises all the empirical evidence from studies that meet prespecified eligibility criteria to answer a specific research question. As part of the ...

Existing reporting checklists lack the specificity and comprehensiveness required to effectively guide the documentation of acupuncture case reports. Therefore, we developed a reporting guideline ...

There is a balance when determining the sample size of a new study: with too few participants, the study may not detect an effect; with too many, some participants may undergo inferior treatments ...