Atypical lymphocytes that survive genetic damage likely undergo more mutations. Clonal expansion of these mutated cells may subsequently promote their progression into malignant lymphomas.

Lymphocyte differentiation articles from across Nature Portfolio Lymphocyte differentiation is a process in which activated B cells or T cells become specialized immune cells.

Lymphocyte activation occurs when lymphocytes (B cells or T cells) are triggered through antigen-specific receptors on their cell surface. This causes the cells to proliferate and differentiate ...

Abstract and Introduction Abstract Cutaneous T cell lymphomas (CTCL) represent a heterogeneous group of T-cell malignancies that manifest primarily in the skin. By far the most common variant of ...