The EMBO Journal4d
Identifying T-cell clubs by embracing the local harmony between TCR and gene expressions
TCRclub integrates scRNA-seq and scTCR-seq data by local harmony to identify functionally similar T cell groups, termed ...
The EMBO Journal4d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal3d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal7d
Genetic linkage disequilibrium of deleterious mutations in threatened mammals
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The impact of negative selection against ...
The EMBO Journal8d
Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The first step of successful infection by any ...
The EMBO Journal7d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Regulation of glucose levels during insulin-evoked hypoglycemia is impaired in patients with diabetes and can lead to a condition called hypoglycemia-associated autonomic failure (HAAF). The ...
The EMBO Journal7d
STAG2 loss in Ewing sarcoma alters enhancer-promoter contacts dependent and independent of EWS::FLI1
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cohesin complexes carrying STAG1 or STAG2 ...
The EMBO Journal8d
Local translatome sustains synaptic function in impaired Wallerian degeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. After injury, severed axons separated from ...
The EMBO Journal8d
Single-nucleus RNA-seq dissection of choroid plexus tumor cell heterogeneity
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The genomic, genetic and cellular events ...
The EMBO Journal7d
Brain mitophagy in space and time
The selective turnover of mitochondria via autophagy, known as mitophagy, is a major quality control mechanism safeguarding eukaryotic cells, including highly specialized neurons in the mammalian ...