The EMBO Journal4d
Identifying T-cell clubs by embracing the local harmony between TCR and gene expressions
TCRclub integrates scRNA-seq and scTCR-seq data by local harmony to identify functionally similar T cell groups, termed ...
The EMBO Journal4d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal7d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
The EMBO Journal10d
Luteolin detoxifies DEHP and prevents liver injury by degrading Uroc1 protein in mice
Luteolin acts as a powerful drug that enhances the detoxification of DEHP by targeting Uroc1 in the mouse liver, thus ...
The EMBO Journal9d
Brain mitophagy in space and time
A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...
The EMBO Journal3d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal10d
Liver DE(HP)toxification: luteolin as “phthalates-cleaner” to protect from environmental pollution
Environmental pollution is a major health problem that affects the health of individuals worldwide and is cumulative with ...
The EMBO Journal1d
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Poly(ADP-ribose) polymerase 1 (PARP1) is one ...
The EMBO Journal2d
The USP12/46 deubiquitinases protect integrins from ESCRT-mediated lysosomal degradation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The functions of integrins are tightly ...
The EMBO Journal4d
Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Severe fever with thrombocytopenia syndrome ...
The EMBO Journal4d
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipid droplets (LDs) serve as crucial hubs for ...
The EMBO Journal7d
STAG2 loss in Ewing sarcoma alters enhancer-promoter contacts dependent and independent of EWS::FLI1
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cohesin complexes carrying STAG1 or STAG2 ...