Structural models of PLD3 and PLD4, enzymes that degrade nucleic acids in the cytoplasm. The enzymes' active (or binding) sites are indicated with black arrows. LA JOLLA, CA—When nucleic acids like ...

Kopan and colleagues previously found the enzyme also is required for another protein called Notch to function. Notch helps produce many cell types and, using a thymus organ culture model system, ...

Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now researchers at Chalmers University of Technology have developed a computer model ...

Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of ...

Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning. The models also can show how genetic mutations alter the enzymes' behavior in ways that ...

A team from the University of Illinois has developed a modeling framework connecting enzyme activity related to photosynthesis to yield. This is the first time a model has tied the dynamic ...

responsible for Alzheimer's -- connected to an inhibitor. The memapsin 2 inhibitor was created in a test tube by have too much A-beta, which causes plaques and tangles that kill brain cells used for ...

The inhibition of an enzyme associated with neurodegeneration processes reduced the toxic effect of tau, one of the proteins that damage neurons in Alzheimer’s disease (AD). A group of scientists from ...

Ridge Biotechnologies (Ridge Bio), a company pioneering enzyme and targeted drug design to power the next wave of precision ...