News

JSTOR Daily8y

Teaching of Limit and Derivative Concepts in Beginning Calculus by Combinations of Inductive and Deductive Methods

The purpose of the research was to compare the teaching of the limit and derivative concepts by inductive and deductive methods to advanced high school students in Chicago suburbs. An analysis of ...
JSTOR Daily1y

On Robust Kernel Estimation of Derivatives of Regression Functions

When estimating derivatives of regression functions from noisy data, a number of additional problems arise compared with the estimation of the regression function itself. Linear methods, such as ...
Nature16y

Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells

The aim of our study was to investigate antiproliferative effects of PEP005 in a panel of colon cancer cell lines that expressed various levels of PKCδ and to evaluate the effects of PEP005-based ...
Risk6y

Polynomial upper and lower bounds for financial derivative price functions under regime-switching

We present a new approach to bounding financial derivative prices in regime-switching market models from both above and below. We derive sufficient conditions under which a particular class of ...
Odessa American4y

Joint feasibility assessment of Bionomics’ BNC210 and EmpathBio’s MDMA derivative EMP-01 treatment regimen for PTSD

ADELAIDE, Australia, Feb. 17, 2021 /PRNewswire/ — Bionomics Limited (ASX: BNO, OTCQB: BNOEF, Germany: AU000000BNO5) (Bionomics) today announced that it has entered into a Memorandum of Understanding ...
Nature22y

Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD

The 4-aminoquinolines, chloroquine and hydroxychloroquine, can suppress chronic graft-versus-host disease (GVHD) following blood and marrow transplantation (BMT) in mice and humans, respectively. We ...