gut.bmj8h
Development and validation of a model to predict survival in colorectal cancer using a gradient-boosted machine
Objective The success of treatment planning relies critically on our ability to predict the potential benefit of a therapy. In colorectal cancer (CRC), several nomograms are available to predict ...
gut.bmj7d
Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-3989
Background and aims RNA interference has been extensively explored in patients with chronic hepatitis B (CHB) infection. We aimed to characterise the long-term efficacy of small interfering RNA (siRNA ...
gut.bmj8d
Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Background Cholangiocarcinoma (CCA) is a very difficult-to-treat cancer. Chemotherapies are little effective and response to immune checkpoint inhibitors is limited. Therefore, new therapeutic ...
gut.bmj9d
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy
2 Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China Background Tumourigenesis in right-sided and left-sided colons demonstrated ...
gut.bmj1d
Detection of Barrett’s oesophagus through exhaled breath using an electronic nose device
Timely detection of oesophageal adenocarcinoma (OAC) and even more so its precursor Barrett’s oesophagus (BO) could contribute to decrease OAC incidence and mortality. An accurate, minimally-invasive ...
gut.bmj2d
Intestinal ganglioneuromatosis and multiple endocrine neoplasia type 2B: implications for treatment
Dr V V Smith, Histopathology, Camelia Botnar Laboratories, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK. Three infants, who presented with intestinal obstruction due to ...
gut.bmj1d
IDDF2023-ABS-0100 Odoribacter. splanchnicus alleviate colitis by regulating neutrophil extracellular traps formation
1 Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, China 2 Department of Gastroenterology and Hepatology, ...
gut.bmj1d
Acute toxic gastric mucosal damage induced by Lugol’s iodine spray during chromoendoscopy
1 Department of Gastroenterology, The General Infirmary at Leeds, Leeds, UK 2 Department of Histopathology, The General Infirmary at Leeds, Leeds, UK 3 Department of Gastroenterology, The General ...
gut.bmj7d
Milk polar lipids reduce lipid cardiovascular risk factors in overweight postmenopausal women: towards a gut sphingomyelin-cholesterol interplay
3 Université Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, CRNH Auvergne, 63000, Clermont-Ferrand, France 4 Université Clermont Auvergne, CNRS, SIGMA Clermont, Institut Pascal, 63000, ...
gut.bmj6d
Impairment of spermatogenesis and sperm motility by the high-fat diet-induced dysbiosis of gut microbes
Objective High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm production. We aim to investigate if HFD-induced gut microbiota dysbiosis can functionally influence ...
gut.bmj6d
Disrupted spermatogenesis in a metabolic syndrome model: the role of vitamin A metabolism in the gut–testis axis
Objective Effects of the diet-induced gut microbiota dysbiosis reach far beyond the gut. We aim to uncover the direct evidence involving the gut–testis axis in the aetiology of impaired ...
gut.bmj5d
Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction
Objective An international meeting was organised to develop consensus on (1) the landmarks to define the gastro-oesophageal junction (GOJ), (2) the occurrence and pathophysiological significance of ...