Experts highlight “nociplastic pain,” a newly defined pain mechanism changing how chronic pain is understood and treated Many chronic pain patients suffer not from damage, but from a sensitized ...

Researchers at Tulane University have identified a previously unknown mechanism that activates pain signaling in the nervous system, a discovery that could reshape future drug development and offer ...

For decades, statins have been the quiet workhorses of cardiology, cutting heart attack and stroke risk for millions while ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer ...

Tris Pharma Showcases a Novel Mechanism of Dual-NOP/MOP (NMR) Agonism for the Treatment of Moderate-to-Severe Acute Pain and Encores Positive Phase 3 Data at 2025 Annual PAINWeek Meeting in Las Vegas ...

Nearly everyone is familiar with the feeling of accidentally touching a hot vessel or holding onto something freezing for too long. Normally, pain serves to protect from potential harm, but when the ...

In a study published in Science, researchers at Karolinska Institutet describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side ...

In a laboratory at the Hebrew University of Jerusalem, Alexander Binshtok, a pain neurobiologist, and his group peer into rodent brains to understand the mechanisms of pain. But that isn’t what he ...

Musculoskeletal pain is one of the more common reasons patients visit their healthcare providers and is easily the most common complaint among those who see physical therapists and chiropractors. One ...