Blood 121(3), 476–484 (2013). IL-15 is a cytokine that stimulates the proliferation of NK and T cells. Previous studies have shown that IL-15 is critical to the induction of T-cell large ...

the IL-21 NK cells exhibited a stronger metabolic fitness than those expressing IL-15. Previous research by MD Anderson ...

In addition, through their expression of the Fc receptor CD16, NK 3.3 cells mediate antibody dependent cellular cytotoxicity (ADCC). When activated by cytokines, such as IL-2 or interferons IL-12 or ...

These findings suggest that KIR2DS2-positive (KIR2DS2+) natural killer (NK) cells could be an attractive therapeutic target ...

ImmunityBio has around $130.1 million in cash, enough to fund operations for at least the next 12 months. Read why I'm very ...

mAb technology has the capability to create distinct agents that can bind to virtually any antigen on the tumor cell surface ... cell transplantation and IL-15 NK cell infusion for paediatric ...

Immunotherapy innovator ImmunityBio, Inc. (NASDAQ: IBRX), announced today that the first patients have been dosed in an ...

IL-2 and IL-15 receptor complexes share the β and γ ... recombinant IL-2 protein also enables the proliferation of mitogen-activated T cells and NK cells, the culture of IL-2 dependent T-cell ...

Safety and accessibility are paramount in autoimmune disease, and we believe that an off-the-shelf, engineered NK cell therapy ... for enhanced cell targeting and a proprietary, membrane-bound form of ...

In 2010, a milestone was achieved when the first patient with cancer was treated with CAR-T-cell therapy. This pioneering treatment modifies a patient's T cells by inserting a gene for a chimeric ...

Our other products for T cell activation and expansion: GMP Grade anti-CD3 Antibody, GMP Grade Anti-human CD3/CD28 magnetic beads, GMP Grade IL-2, IL-7, IL-15, IL-21, etc. 2. Enhance NK cell ...

Less frequent IV dosing with nemvaleukin in patients with select advanced solid tumors, including ovarian cancer and mucosal melanoma, showed ...