The course of three patients indicated that both types of reaction, Shwartzman and Arthus-like, can occur in hyperacute rejection of human-kidney allografts and that the late histologic appearances ...

Biopsies of renal transplants taken within one hour after completion of vascular anastomoses revealed, in seven of 132 cases, the accumulation of large numbers of polymorphonuclear leukocytes within ...

Rejection was avoided for a few days using novel protocols. A pioneering technique has led to conversion of a human blood type-A donor kidney to type-O for transplantation into a type-O patient with ...

Xenotransplants, or xenografts, are viewed as one solution to the growing problem of the inadequate supply of human organs and as a source of cells, tissues, and organs that show promise for treating ...

The first successful human transplant of a kidney converted from blood type A to universal type O used special enzymes developed at the University of British Columbia to help prevent a mismatch and ...

Two reports on the knockout of one allele of the α1,3-galactosyltransferase gene in pigs bring us one step closer to the transplantation of pig organs into people. The α1,3GT gene encodes an enzyme ...

Recent advances using transgenic animals or exogenous complement inhibitors have demonstrated prevention of hyperacute rejection of vascularized organs, but not graft loss due to acute vascular ...