Researchers showed that whole-genome bisulfite sequencing, EM-seq, and the biomodal evoC kit are all feasible for DNA methylation profiling of low-input archival FFPE triple-negative breast cancer ...
DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...
Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.
A new computational framework called JEEPERS detects and corrects methylation errors caused by jagged ends in cell-free DNA, ...
Somatic mutations, the DNA changes that occur as our bodies grow and age, not only hold an important key to cancer but are emerging as the seeds of a wide range of common, noncancerous diseases. The ...
Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...
Have you ever come across the term "NGS" in articles about cancer gene panel testing or whole-genome analysis?NGS is a ...
DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...
Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...
Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...
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