Major depression is not only a crisis of mood, it is also a crisis of biology that reshapes the brain itself. As genetic ...
Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...
A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.
Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...