A new study published in Cell extends previous biochemical characterization of the fission-yeast cohesin complex to show that there are marked similarities in the mechanisms of DNA entry to and exit ...

The role of cohesin, its regulation, as well as its recently identified function as a potential driver or facilitator for tumors has been explained and revised by an international expert in cohesin.

A cohesin molecule ensures the proper distribution of DNA during cell division. Scientists can now demonstrate the concept of its carabiner-like function by visualizing for the first time the open ...

In recent years it has become evident that the spatial organisation of the genome is key for its function. This organisation depends on a number of factors, the cohesin protein complex being one of ...

Researchers have uncovered a fundamental rule that governs how genes are physically arranged inside the cell nucleus, and how ...

Ana Losada, from the Spanish National Cancer Research Centre (CNIO), is the scientist who identified cohesin in vertebrates, a protein that is essential in cell division. Losada has studied cohesin ...

Premature ovarian failure is a major cause of female infertility. The genetic causes of this disorder remain unknown in most patients. Using whole-exome sequence analysis of a large consanguineous ...

Scientists at Nagoya University, with colleagues at Kyoto University in Japan, have uncovered a mechanism that allows a protein complex to bind to DNA without impeding some of the important processes ...

Best known for its ability to regulate the separation of sister chromatids during cell division, the cohesin protein complex, a ring-shaped structure, has shown that it has other powers, such as the ...

A study by Fena Ochs, new Group Leader and Associate Professor at Biotech Research & Innovation Center (BRIC) University of Copenhagen, delves deep into the intricate world of cell division. The study ...