After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta ...

Enzymes are regarded as the key to sustainable chemistry. Despite major advances in protein design, creating artificial ...

Proteins and peptides are the primary functional polymers of medical biochemistry, directing virtually all cellular processes through their structural diversity, catalytic activities and signalling ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structure of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases. The ...

In the ERC project HelixMold, a team from TU Graz developed a method for the computer-based design of artificial proteins, with a focus on custom biocatalysts for pharmaceutical applications or the ...

Proteins, the cell’s principal molecular machines, drive a vast spectrum of biological processes. Deciphering how sequence dictates structure and function—the sequence–structure–function (SSF) ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics. Many ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...

An illustration of one of Grove Biopharma’s protein-like polymers in sky blue and bright yellow. These protein-like polymers may help target intractable cancer-causing proteins. Credit: Saeed Najafi, ...

Researchers at the University of Greifswald have discovered a new mechanism by which bacteria such as Bacillus subtilis can regulate the production of the central metabolic molecule acetyl coenzyme A ...