Beta-lactamases constitute a diverse family of enzymes that underlie the most widespread mechanism of resistance to β-lactam antibiotics in Enterobacteriaceae. Continuous exposure to penicillins, ...
Extended-spectrum beta-lactamases (ESBLs) have emerged as a major mechanism of resistance among Gram-negative pathogens, notably Escherichia coli and Klebsiella pneumoniae. These enzymes hydrolyse ...
In a recent study published in the Microbiology Spectrum Journal, researchers suggest that Escherichia coli ST2797 could potentially be a new type of extended-spectrum beta-lactamase (ESBL) ...
Resistance to carbapenems among Enterobacterales is primarily achieved by production of carbapenemases, which are enzymes capable of hydrolyzing carbapenem antibiotics and most other beta-lactams and ...
Enzyme-catalysed antibiotic degradation, or modification or degradation of antibiotics or their targets, is one of the major mechanisms of antibiotic resistance. Plasmid borne genes encoding modifying ...
Ad hoc announcement pursuant to Art. 53 LRAllschwil, Switzerland, August 05, 2026Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a ...
Antibiotic treatment disrupts the balance of beneficial and harmful bacteria in a person's gut. That disruption can lead to the overgrowth of fungal species in the gut mycobiota, including the common ...
Lately I have become intrigued by the word, innovation. Innovation is used as a criterion for funding grants, for status in reviews of our antibiotic pipeline, for intelligence, imagination and many ...
Antibiotic treatment disrupts the balance of beneficial and harmful bacteria in a person's gut. That disruption can lead to the overgrowth of fungal species in the gut mycobiota, including the common ...
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