Toksook Bay is a city and village on Nelson Island in Bethel Census Area, Alaska. The population was 590 at the 2010 census, up from 532 in 2…Toksook Bay is a city and village on Nelson Island in Bethel Census Area, Alaska. The population was 590 at the 2010 census, up from 532 in 2000. As of 2018, the estimated population was 667, making it the largest village on the island.